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BNOAT Oncology, Inc. is an oncology research and development company founded by renowned cancer researcher, Dr. Joseph A. Bauer, a Professional Staff Alumnus of the Cleveland Clinic Taussig Cancer Center (ranked top 10 in the United States by US News & World Report).
The company has the exclusive license to develop nitrosylcobalamin (NO-Cbl), a vitamin B12-based, "Trojan Horse"- anti-tumor agent.
BNOAT Oncology, Inc. will advance the clinical development of NO-Cbl a tumor-targeting, non-toxic anti-cancer agent with the goal of significantly improving the standard of care in both cancer treatment and prevention worldwide in both humans and animals.
Extensive research as shown that NO-Cbl functions as a “Trojan Horse” by deceiving cancer cells into taking up a toxic payload and ultimately causing cell death. The Developmental Therapeutics Program (DTP) of the National Cancer Institute (NCI) independently validated the anti-tumor properties of NO-Cbl in 60 different human cancer cell lines.
The results of Dr. Bauer’s dog studies received international media attention and were featured in US News and World Report, Forbes, Web MD, MSNBC Health and Medicine, the American Chemical Society and in several local news programs and newspapers. NO-Cbl significantly reduced the size of the tumors (65% on average) in all of the dogs and in some dogs completely eliminated the tumor altogether. NO-Cbl increased the life span of each animal and improved its quality of life without the adverse side effects commonly associated with current chemo or radiation therapy regimes.
BNOAT Oncology, Inc. contract research labs produce kilogram quantities of cGMP NO-Cbl utilizing a specially trained, GMP manufacturing team that operates under the USFDA Guidelines for Bulk Pharmaceutical Chemicals (BPC), www.fda.gov, and is backed by a comprehensive documentation system.
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